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博导、教授、留日博士。1998年至2003年留学日本Hiroshima University,获分子生物学专业博士学位,并从事博士后研究工作。现任“工业微生物发酵技术国家地方联合工程研究中心”主任、“工业微生物教育部工程研究中心”主任,“福建省现代发酵技术工程研究中心”主任,福建师范大学生命科学学院副院长。任“中国生物化学与分子生物学会工业生化与分子生物学分会”副理事长,“教育部高等学校生物工程与生物技术专业教学指导委员会”委员,“福建省生物化学学会”常务副理事长,福建省重点学科“发酵工程”学科带头人;入选福建省“百千万人才工程”,福建省高等学校新世纪优秀人才,福建省青年科技标兵。 从事微生物功能基因和工业酶制剂的研发工作。先后主持参与国家“863”、国家自然科学基金、国家支撑计划、国家火炬高新技术、福建省重大专项、福建省自然科学基金重点和省发改委产业重大等23项课题的研究。获国家发明金奖1项,省科技进步二等奖2项,省科技进步三等奖1项,省自然科学优秀论文一等奖1篇,中国科协优秀学术论文奖1篇。已在《Bioresource Technology》、《Marine Biotechnology》、《Journal of Biotechnology》、《Journal of Molecular Catalysis B-enzymatic》、《Curr Microbiol Enzyme and Microbial Technology》、《Journal of Bioscience and Bioengineering》、《Appl.Biochem Biotechnol》和《微生物学报》、《生物工程学报》等国内外刊物上发表120多篇论文,并在GenBank数据库登录基因序列4200多条。重视成果产业化,建立了多个产学联合体。 代表论文: (1)Li-Na Qin, Fu-Rong Ca, Xin-Rui Dong, Zhen-Bang Huang, Yong Tao, Jian-Zhong Huang*, Zhi-Yang Dong*. Improved Production of Heterogenous Lipase in Trichoderma reesei by RNAi mediated Gene Silencing of an Endogenic Highly Expressed Gene. Bioresource Technology, 2012, 109:116-122. (2)Zheng-Yu Shu, Ji-Guang Wu, Lan-Xing Cheng, De Chen, Yong-Mei Jiang, Xin Li, Jian-Zhong Huang*. Production and characteristics of the whole-cell lipase from organic solvent tolerant Burkholderia sp. ZYB002. Appl. Biochem Biotechnol, 2012, 166:536–548 (3)Zhengyu Shu, Jiguang Wu, De Chen, Lanxing Cheng, Yi Zheng, Jianping Chen, Jianzhong Huang*. Optimization of Burkholderia sp. ZYB002 lipase production for pitch control in thermomechanical pulping processes. Holzforschung, 2012,dio10.1515/HF.2011.152 (4)Jian-Zhong Huang*,Xian-Zhang Jiang,Xiao-Feng Xia,Ai-Qun Yu, Ruo-Yu Mao,Xiao-Feng Chen,Bao-Yu Tian. Cloning and functional identification of delta5 fatty acid desaturase gene and its 5′-upstream region from marine fungus Thraustochytrium sp. FJN-10. Marine Biotechnology,2011,13(1):12-21. (5)Zhengyu Shu,Jiguang Wu,Longyin Xue,Ruifeng Lin,Yongmei Jiang,,Lianghua Tang,Xin Li,Jianzhong Huang*. Construction of Aspergillusniger lipase mutants with oil-water interface independence. Enzyme and Microbial Technology,2011,48(2):129-133. (6)Yong-Biao Zheng, Dang-Xia Chen, Jun-Jing Li, Jiang-Zhong Huang*. New Sesquiterpenoid from Pestalotiopsis sp. Chinese Journal of Natural Medicines, 2011, 9 (6): 421−424 (7)Zheng-Yu Shu,Huan Jiang,Rui-Feng Lin,Yong-Mei Jiang,Lin Lin,Jian-Zhong Huang∗. Technical methods to improve yield,activity and stability in the development of microbial lipases. Journal of molecular catalysis B-enzymatic,2010,62(1):1–8. (8)Bao-Yu Tian,Qin-Geng Huang,Yan Xu,Chun-Xiang Wang,Rui-Rui Lv,Jian-Zhong Huang*. Microbial community structure and diversity in a native forest wood-decomposed hollow-stump ecosystem. World J Microbiol Biotechnol,2010,26(2):233–240. (9)Wei Huang,Bao-Yu Tian,Jing Guo,Wan-Ling Cai,Jian-Zhong Huang*. Production of an In Vitro-Derived Deletion Mutation of Brevibacillus laterosporus by Constructing a Homology-Driven Integration Vector. Curr Microbiol,2010,61(5):401-406. (10)Chenggang Xu, Yong Qin, Yudong Li, Yuetong Ji, Jianzhong Huang, Houhui Song, Jian Xu. Factors influencing cellulosome activity in Consolidated-Bioprocessing of cellulosic ethanol. Bioresource Technology, 2010, 101(24):9560–9569 (11)Yi-Ming Tao, Xiang-Zhi Zhu, Jian-Zhong Huang, Su-Juan Ma, Xiao-Bing Wu, Min-Nan Long, Qing-Xi Chen. Purification and properpties of endoglucanase from a sugarcane bagasse hydrolyzing strain Aspergillus glaucus XC9. Agricultural and Food Chemistry, 2010, 58(10):6126-6130. (12)Zhengyu Shu, Ruifeng Lin, Huan Jiang, Yanfeng Zhang, Mingzi Wang, and Jianzhong Huang*. A rapid and efficient method for directed screening of lipase-producing Burkholderia cepacia complex strains with organic solvent tolerance from rhizosphere. Journal of bioscience and bioengineering,2009,107(6):658-661. (13)Bao-Yu Tian,Chong-Rong Ke,Wei Huang,Ke-Qin Zhang,Jian-Zhong Huang*. Direct visualization of bacterial infection process in nematode hosts by an improved immunocytochemical method. World J Microbiol Biotechnol,2009,25:909–912. (14)Baoyu Tian,Wei Huang,Jianzhong Huang,Xianzhang Jiang,Lina Qin. Investigation of protease-mediated cuticle-degradation of nematodes by using an improved immunofluorescence-localization method. Journal of Invertebrate Pathology,2009,101:143–146. (15)Jianzhong Huang*,Xianzhang Jiang,Xiaowei Zhang,Weihua Chen,Baoyu Tian,Zhengyu Shu,Songnian Hu. Expressed sequence tag analysis of marine fungus Schizochytrium producing docosahexaenoic acid. Journal of Biotechnology,2008,138:9–16. (16)Jianzhong Huang,Tsunehiro Aki,Toshihiro Yokochi,Toro Nakahara,Daiske Honda,Seiji Kawamoto, Seiko Shigeta,Kazuhisa Ono,Osamu Suzuki. Grouping Newly Isolated Docosahexaenoic Acid-Producing Thraustochytrids Based on Their Polyunsaturated Fatty Acid Profiles and Comparative Analysis of 18S rRNA Genes. Marine Biotechnology,2003,5(5):450-457. (17)Jianzhong Huang,Tsunehiro Aki,Kazutaka Hachida,Toshihiro Yokochi,Seiji Kawamoto,Seiko Shigeta,Kazuhisa Ono,Osamu Suzuki. Profile of Polyunsaturated Fatty Acids Produced by Thraustochytrium sp. KK17-3. Journal of the American Oil Chemist’s Society,2001,78(6):605-610. (18)Jianzhong HUANG,Tsunehiro AKI, Seiji KAWAMOTO, Seiko SHIGETA,Kazuhisa ONO,Osamu SUZUKI. Enzymatic Preparation of Glycerids Rich in Docosahexaenoic Acid from Thraustochytrid Single Cell Oils by Candida rugosa Lipase. Journal of Oleo Science,2002,51(7):447-455. (19)Jianzhong Huang, Xianzhang Jiang. Cloning and Expression Two △6-Desaturase Isozymes from Mucor. Acta Biochim et Biophy.Sinica,2004,36(2):164-165. (20)江贤章,秦丽娜,田宝玉,舒正玉,黄建忠*. 海洋破囊壶菌Thraustochytrium sp.FJN-10 DHA生物合成途径相关延长酶的克隆与表达.微生物学报,2008,48(2):176-183. (21)陈的,舒正玉,薛龙吟,林瑞凤,吴继光,蒋咏梅,李欣,林跃鑫, 黄建忠*. 不依赖油水界面激活的黑曲霉脂肪酶突变体的构建. 生物工程学报,2011,27(6):860-867. (22)林晓华,柯崇榕,吴毕莎,郑永标,李力,陈由强,黄建忠*. 酿酒酵母SNF4基因敲除缺失菌株的构建. 生物工程学报,2011,27(4): 572-578. (23)强慧妮,杨欣伟,田宝玉,柯崇榕,林伟铃,吕睿瑞,黄薇,王春香,黄建忠*.黑曲霉果胶裂解酶基因在毕赤酵母Pichia pastoris GS115中的表达. 生物工程学报,2009,25(12):1962-1968. (24)郑海英,黄平,柯崇榕,蔡少丽,林国滟,黄建忠*.特异腐质霉内切葡聚糖酶Ⅱ基因在毕赤酵母中的表达及酶学性质.微生物学通报,2012,39(2): 145−153 (25)宋芬芬,江贤章,陈清霞,黄建忠*. 毛霉△6-脂肪酸脱氢酶随机突变文库的构建与分析. 微生物学通报,2011,38(5):694-701. (26)吴继光,舒正玉,程蓝骍,江 欢,祝昌飞,黄建忠*. 耐受有机溶剂洋葱伯克霍尔德菌ZYB002全细胞脂肪酶酶学性质. 微生物学通报,2010,37(1):2-6. (27)江欢,舒正玉,吴继光,黄平,黄建忠*.耐有机溶剂极端微生物的耐受机制及应用.微生物通报,2009,36(11):1744-1749. (28)舒正玉,林瑞凤,江欢,张岩峰,黄建忠*. 从植物根际定向批量筛选广谱有机溶剂耐受性脂肪酶产生菌. 微生物学通报,2009,36(6):809-814. (29)舒正玉,薛龙吟,林瑞凤,蔡少丽,黄建忠*. 新型微生物脂肪酶资源开发. 微生物学通报,2009,36(5):747-752. (30)刘海英,王娟,舒正玉,吴松刚,黄建忠*. 长梗木霉内切葡聚糖酶Ⅰ基因的克隆及其在毕赤酵母中的表达. 微生物学通报,2009,36(3):355-359. (31)王艳尊,雷娟娟,江贤章,高媛媛,李欣,蓝灿华,陈由强,陈如凯,黄建忠*.酿酒酵母adh2和ald6双基因缺失突变株的构建.微生物学通报,2009,36(2):211-216. (32)秦丽娜,江贤章,田宝玉,舒正玉,黄建忠*. 酿酒酵母乙醇脱氢酶I基因的超表达. 微生物学通报,2008,35(2):261-266. (33)李志平,江贤章,田宝玉,舒正玉,黄建忠*. 裂殖壶菌酰基载体蛋白(ACP)基因的克隆与表达. 微生物学通报,2008,35(2):256-260. (34)陈金卿, 江贤章,刘丽霞,黄建忠*. 海洋破囊壶菌△4-脂肪酸脱饱和酶基因在酿酒酵母中的表达. 微生物学通报,2007,34(6):1154-1157. (35)宋浩雷,郭晓贤,王艳尊,江贤章,黄建忠*. 敲除SFA1基因提高酿酒酵母乙醇合成能力的研究. 微生物通报,2007,34(3):421-425. (36)林瑞凤,舒正玉,薛龙吟,江欢,黄建忠*. 微生物脂肪酶蛋白质工程. 中国生物工程杂志,2009,29(9):108-113. |